The After Cancer Blog

Do you ever feel anxious, unsteady, and overwhelmed before a medical test or while waiting for results? I used to be the same way. My journey with cancer and an autoimmune disease taught me how powerful our emotions can be and how they affect our health. In the same month, I was diagnosed with a rare autoimmune disease and breast cancer. It felt like my world was falling apart. My heart raced, I couldn't focus, and I was consumed by constant worry. Desperate for relief, I discovered HeartMath, a system that uses heart rate variability (HRV) to help manage stress and anxiety . Discovering HeartMath as a Cancer Survivor HeartMath became a lifeline for me. By using HRV biofeedback and specific techniques, I found a way to manage my anxiety and stay positive. One of the most effective methods I used was the Heart Lock-In Technique. Practicing this daily, I noticed an immediate shift from emotional chaos to a state of calm. My mind cleared, and I could focus better. As I continued using these techniques, I experienced the profound benefits of emotional regulation. This encouraged me to become a certified HeartMath provider through the HeartMath Institute, an organization dedicated to this science-based system for over 30 years. What is HeartMath? HeartMath is a science-based system that combines evidence-based techniques with HRV technology to enhance self-regulation. This approach helps align the mind, body, and emotions , building resilience and promoting overall well-being. Over 400 peer-reviewed journal articles have documented the benefits of using HeartMath’s HRV biofeedback. These benefits include improved attention and mental clarity, reduced pain, increased energy levels, and better sleep . The Importance of Coherence Coherence is a physiological state crucial for building resilience and maintaining mental, emotional, and physical health. It describes a system, including the human body, where all parts are harmoniously connected and functioning optimally. In a coherent state, no energy is wasted because the heart, lungs, nervous system, endocrine system, and immune system are synchronized and working efficiently. The Quick Coherence Technique One simple HeartMath technique is the Quick Coherence Technique. This method helps you shift from negative to positive emotions, bringing your body back into coherence. Here’s how to practice it: Step 1: Heart-Focused Breathing™ Focus your attention on your heart. Imagine your breath is flowing in and out of your heart or chest area, breathing a little slower and deeper than usual. Find a comfortable rhythm. Step 2: Activate a Positive or Renewing Feeling While heart-focused breathing, try to experience a regenerative feeling like appreciation or care for someone or something in your life. Here are some ideas to help you activate these feelings: Think of someone you feel grateful for. Recall a time when you did something you felt proud of. Imagine a place where you feel safe or good. Think of your pet or something your pet likes to do. Remember something that makes you laugh. Focus on a feeling of calm or ease. Practicing this technique regularly helps your body achieve coherence, promoting healing at a cellular level. When the heart and brain communicate effectively, you experience calm, reduced anxiety, decreased mental chatter, and a greater sense of presence. The Science Behind HeartMath The HeartMath Institute has conducted extensive research on the benefits of HRV and coherence. Their findings show that achieving coherence improves physical and emotional health. For cancer patients, this can mean better stress management, improved immune function, and a greater ability to cope with treatment and recovery. My Personal Journey with HeartMath Using HeartMath has been transformative in my healing journey. Not only did it help me manage my anxiety, but it also provided a sense of control over my emotions and health. The techniques allowed me to focus on healing rather than being consumed by fear and worry. As a certified HeartMath wellness provider, I now help others navigate their health challenges. Teaching these techniques to fellow cancer patients and individuals with chronic illnesses has been incredibly rewarding. Seeing others benefit from these simple yet powerful tools reaffirms my belief in the power of HeartMath. Practical Applications for Cancer Patients For those dealing with cancer, the stress and anxiety can be overwhelming. HeartMath offers a practical way to manage these emotions and improve overall well-being. Here are some tips for incorporating HeartMath into your daily routine: Start with the Basics: Begin with the Quick Coherence Technique. Practice it daily, especially during stressful times. Consistency is Key: Like any skill, regular practice enhances the benefits. Aim to practice HeartMath techniques multiple times a day. Track Your Progress: Use HRV biofeedback tools to monitor your coherence levels. This feedback can be motivating and help you see your progress. Join a Support Group: Connecting with others who use HeartMath can provide additional support and encouragement. Work with a Certified Provider: If possible, work with a certified HeartMath provider who can offer personalized guidance and support. Living with cancer and chronic illness is challenging, but tools like HeartMath can make a significant difference. By practicing these techniques, you can manage stress, improve emotional regulation, and support your body’s healing process. As someone who has walked this path, I can attest to the transformative power of HeartMath. It has not only helped me survive but also thrive in the face of adversity. If you’re dealing with cancer or any chronic illness, I encourage you to explore HeartMath. It might just be the tool you need to navigate your journey with more ease and resilience.

The Myth: cancer survivors shouldn’t eat soy One persistent myth in the realm of nutrition and health is the belief that consuming soy can increase the risk of breast cancer and even prostate cancer . This misconception has caused many people to avoid soy products out of fear that they could contribute to cancer development. The Facts: Breast Cancer & Soy The concern over soy and breast cancer largely stems from earlier studies that sought to establish a correlation between soy consumption and breast cancer risk. These studies were often inconclusive and led to confusion and concern. However, as scientific research has advanced, our understanding of soy and its effects on breast cancer has become clearer. Soy contains compounds known as isoflavones, specifically genistein and daidzein. These isoflavones have a structure similar to that of 17-β estradiol, a form of estrogen found in human females. Because of this similarity, isoflavones can bind to and activate estrogen receptors in the body. However, rather than increasing estrogen production, these isoflavones actually result in a decrease in the body's estrogen production. Recent studies have shown that not only soy consumption doesn’t increase breast cancer risk, but it may actually be beneficial for breast cancer prevention. Women who consume high amounts of soy and isoflavones have been found to have a lower risk of being diagnosed with breast cancer compared to women who do not include soy in their diets. This suggests that soy may play a protective role against the development of breast cancer. A report from the World Cancer Research Fund International/American Institute for Cancer Research concluded that despite the limited number of published studies on the matter, there is sufficient evidence to suggest a positive outcome between soy consumption and breast cancer survival rates. It also reported that higher consumption of soy and, therefore, isoflavones post-diagnosis of breast cancer is associated with a reduced death rate. The Facts: Prostate Cancer & Soy Recent studies indicate a strong link between soy consumption and a reduced risk of prostate cancer (PCa). Epidemiological evidence shows that total soy food intake is significantly associated with a lower risk of developing PCa. While research on individual soy foods and their relationship with PCa risk is limited, tofu has been the most extensively studied. The findings consistently highlight tofu's significant protective association with prostate cancer. This evidence suggests that incorporating tofu and other soy-based foods into one's diet may contribute to a decreased risk of prostate cancer, emphasizing the potential benefits of soy isoflavones in cancer prevention. So, should cancer survivors eat soy or not? The myth that soy consumption increases the risk of breast and prostate cancer is unfounded. On the contrary, incorporating soy into your diet can be beneficial and may lower the risk of both cancers. As with any dietary choice, it is important to consume soy as part of a balanced diet. The latest research supports the safety and potential benefits of soy, providing reassurance to those who enjoy soy-based foods. Written By Luis Guilherme

Cannabis-based drugs have been explored for a range of medical conditions over the past decades. Multiple sclerosis spasticity and seizures are among the cases where we have promising results. But what about cancer patients? To highlight the National CBD Day on this August 8th, let’s discuss the current evidence supporting the use of cannabis drugs for cancer patients, particularly for symptoms such as chemotherapy-induced nausea and chronic pain . What is Cannabis? Cannabis sativa L . is a plant containing over 80 different naturally occurring compounds known as cannabinoids. Two well-known cannabinoids are cannabidiol (CBD) and tetrahydrocannabinol (THC). THC is psychoactive, which means it changes how your brain works. It’s the ingredient in marijuana that makes you feel high. CBD isn’t psychoactive, so it doesn’t make you high. When discussing the pharmaceutical use of cannabis, it is also important to differentiate between cannabis-related compounds and cannabis-derived compounds. Cannabis-related compounds are naturally occurring in the plant and are extracted directly to manufacture drug products. In contrast, cannabis-derived compounds are synthetic and created in a laboratory from the natural ones. Using cannabis to treat chemotherapy-induced nausea and vomiting For example, chemotherapy-induced nausea and vomiting (CINV) have been effectively managed using cannabis-derived compounds like dronabinol (Marinol®/Syndros®) and nabilone (Cesamet®). Both of these medications are derived from the THC and have received approval from the US Food and Drug Administration (FDA) for patients who have not adequately responded to conventional antiemetic treatments. Even though these medications come with some side effects, they have been used as a therapy option for the past decades.     Using cannabis to treat cancer pain However, the discussion becomes more complex when it comes to chronic pain management. There is no cannabis-derived approved medicine for this indication, so it is usually used in the form of inhalation, oils, sprays or tablets containing active cannabis ingredients. Studies and systematic reviews over the past decades have produced inconsistent results. Up to this moment, there are no double-blinded and placebo-controlled clinical trials with large sample sizes that either reject or prove the efficacy of cannabis in the treatment of chronic cancer pain management.  Additionally, in most of the studies that we have to this moment, cannabis is used as an adjunct therapy. This means that patients are also taking conventional painkillers such as opioids, and the goal of the trials is to evaluate if cannabis can reduce the consumption of opioids. In general, these trials suggest that cannabis may have some potential benefits, but the side effects and long-term effects need to be considered. So, for cancer-related chronic pain, despite having some promising results, much needs to be done until we get to a recommendation or clinical guideline. Cannabis-based drugs have a potential but more research needs to be done The exploration of cannabis-based drugs for medical conditions has yielded promising results, particularly in managing symptoms such as chemotherapy-induced nausea and chronic pain. While cannabis-derived compounds like dronabinol and nabilone have proven effective for CINV, the use of cannabis for chronic pain remains contentious and requires further research and clinical guidelines. Additionally, recent studies on CBD highlight its potential not only for symptom management but also as a possible treatment for certain cancers. Although still in early stages, the ongoing research and recognition by institutions like the American Cancer Society suggest a future where cannabis-based therapies could play a role in cancer treatment. Continued research and careful consideration of the benefits and risks will be essential in advancing the medical application of these drugs. If you’re interested in testing cannabis-based products, talk to your Medical Team to get their advice on your individual case. Written By Luis Guilherme

Plants: The birthplace of medicines Before the nineteenth century, what we understood as medicine was mainly plant extracts, infusions and tinctures. So, during all the history of humankind, studying, classifying and understanding the effects of plants on our bodies has been among the most important activities. Pharmacopeias and encyclopedias on medicinal plants date back to ancient Egypt, with the Ebers Papyrus  from 1550 BC. Books such as the Historia Plantarum  by Theophrastus, Aristotle's successor, and De materia medica  by Dioscorides represented the pinnacle of Greek, and consequently medieval, medicine with descriptions of numerous herbal drugs.  Cancer plant-based medicines During the beginning of the nineteenth century, we were able to isolate the first active ingredients. The significance of plants became even more evident. Acetylsalicylic acid (aspirin), quinine and morphine are just some of the examples of drugs isolated from plants that were developed at the end of the 19th century. It took a little longer to find cancer drugs, as we only started seeing some form of drug therapy after the Second World War. But in the 1960s, the development of cancer drugs experienced a renaissance of discoveries with plant-based medicines. A tree that saved millions of lives of people with cancer A perfect example begins with the history of the European yew. The tree is well known throughout history. The Celts and Greeks named it the “tree of death”. Julius Caesar, in his book on the Gallic War, described a situation in which the king of a Celtic tribe, unwilling to fight in a war, used the extract of this tree to commit suicide. Over the course of history, we understood that there was something very poisonous in its bark and leaves.  But there is nothing more attractive to oncologists than a well dosed poison with the potential of killing cancer cells. So, the European yew was rediscovered in the early 1960s through a partnership between the National Cancer Institute and the US Department of Agriculture. In an era where pharmaceutical innovation was no different from the Ford’s factory model, the program coordinated by Dr. Jonathan Hartwell, established a systematic screening and isolation system that included more than 100,000 specimens. From a tree to a best-selling cancer drug Active ingredients called “Taxanes” were isolated from the bark of the European yew. After several chemical processes, this ingredient was going to become the best-selling cancer drug in history. 0.5 g of paclitaxel, also commercially known as Taxol, was extracted from 12 kg of dried yew trunk and bark, which corresponds to a yield of 0.004%. More than 2000 trees had to be felled to obtain 1 kg of paclitaxel. It took more than 20 years between improvements in the synthesis process and clinical trials to get to a commercially viable product. It was not until 1992 that the American company Bristol Myers Squibb submitted an application to the FDA, which was approved in 1994. To this day, paclitaxel and its derivatives such as dotaxel are still the first line treatment of various types of cancer such as ovarian cancer and non-small cell lung cancer. The tree described by Julius Caesar as poisonous and dangerous became one of the most important medicines in modern cancer treatment. The history of paclitaxel is not only the history of a revolutionary drug that has saved the lives of millions of cancer patients over the past decades, but also a great reminder of how important plants are in drug discovery. Keep an eye on your backyard, the next pharmaceutical blockbuster might be waiting there to be discovered. Written By Luis Guilherme

As the CEO of The After Cancer, I’ve had the privilege of attending many events that celebrate cancer patients , but CancerCon 2024 in Austin, Texas, was something truly special. It wasn't just another conference; it was a vibrant, pulsating gathering of patients, survivors, caregivers, and medical professionals, from all walks of life but all united by a common bond—cancer. This year, our team had the opportunity to add a unique flavor to the event, something both irreverent and meaningful, that resonated with everyone who attended. Cards Against Cancer: Breaking the Ice with Laughter One of our contributions to CancerCon was a deck of cards we called Cards Against Cancer , a cheeky nod to the popular game Cards Against Humanity. The idea was born from our desire to bring humor into the lives of those who have faced the unimaginable. Cancer has a way of stripping away the lightness in life, so we wanted to offer a tool that would help people reclaim laughter, even if just for a few moments. We handed out these decks to every attendee, and the response was overwhelmingly positive. Laughter echoed as people huddled around our table, flipping through the cards, sharing the dark humor that only those who have been through the trenches could truly appreciate. It wasn’t just a game; it was a way to build connections, to say, "I understand," without having to say anything at all. The Kayak Adventure: A Moment of Peace and Perspective Before the hustle and bustle of the conference began, we joined a group of patients for a kayak adventure organized by First Descents  on the serene waters of the Colorado River in Austin. As we paddled under the warm Texas sun, surrounded by the beauty of the city, there was a sense of peace that settled over us. It was a moment to breathe, to reflect, and to appreciate the simple act of being alive. As the sun began to set, we gathered under the Congress Avenue Bridge to witness the famous Austin bats take flight. Watching thousands of bats swirl into the evening sky was a powerful reminder of the interconnectedness of life, of how even in the darkest moments, there is wonder. For many of us, it was the perfect way to start the weekend—grounding us in the present, in the here and now, before diving into the emotional depths of the conference. The Unicorn Poster: A Symbol of Defiance At our exhibitor booth, we displayed something that became our iconic image: a giant poster of a unicorn, with a twist—the unicorn's face was a defiant middle finger. It was our way of saying, "Not today, Cancer". This poster became a canvas for the emotions of everyone who walked by. Patients, survivors, and even healthcare providers took turns signing the poster, leaving messages of hope, strength, and sometimes just a simple "F*** cancer." By the end of the conference, the poster was covered with signatures and messages, each one a testament to the shared defiance of a community that refuses to be defined by this disease. The unicorn wasn’t just a quirky piece of art for the event, we'll keep it in our offices as a reminder of all the unique connections we had during CancerCon. Meals and Meaningful Conversations One of the most impactful aspects of CancerCon for me was the opportunity to share meals with some of the attendees. These weren’t just casual conversations; they were moments of profound connection. Over breakfast, lunch, and dinner, we shared our stories—the highs and lows, the victories and setbacks. There were tears, laughter, and moments of silence as we all grappled with the weight of our experiences. The act of sitting down together and opening up to one another created a bond that transcended the conference itself. These are the moments I will carry with me long after CancerCon has ended. Meeting the Nurses: The Unsung Heroes Another highlight was meeting the incredible nurses who had traveled from across the nation to attend CancerCon. These are the people who dedicate their lives to caring for others, often working long hours under immense pressure. The energy they brought to the conference was palpable. It was inspiring to hear their stories, to learn about the challenges they face, and the innovative ways they are finding to provide care. They are the backbone of the cancer community, and their presence at CancerCon was a powerful reminder of the importance of support systems in the journey through illness and recovery. An Inexplicable Buzz The energy at CancerCon, especially from the young adult attendees, was infectious. These are people who are facing a life-altering diagnosis at a time when they’re supposed to be building their futures. The conversations I had with them were eye-opening, as they shared the unique challenges they face: losing their identity, holding it together when everything is falling apart, and the jarring experience of receiving a diagnosis at a time when they’re supposed to be stepping into adulthood. We talked about the mentality shift that cancer forces upon you—how it strips away the trivial and forces you to focus on what truly matters. They spoke about the difficulty in relating to peers who haven’t had the same experiences, and the courage it takes to be vulnerable in a world that often doesn’t understand. As I reflect on the experience, I am filled with gratitude for the people I met, the stories I heard, and the connections I made. Cancer is a brutal adversary, but events like CancerCon remind us that we are not alone—that together, we can face anything, laugh in the face of fear, and, most importantly, live fully in the time we have. About Mariana Arnaut Mariana Arnaut  is the CEO and Co-Founder  of The After Cancer. She has a family history of different cancers (lung, melanoma, esophageal) and a background in digital & innovation. You can reach out to her at mariana@theaftercancer.com .

Science arises from contradiction. Authors battle themselves using evidence as a weapon in order to achieve the so rare “scientific consensus”. From this organized mess we have been able to provide some answers to important matters in the past. To answer the question of whether aluminum in antiperspirants can cause breast cancer , we need to dig deep into one of these debates. Three studies came up with the link between cancer and antiperspirants with aluminum. The first evidence of such a link comes from a 2001 article that found that breast tumors appeared mostly in the upper outer quadrant of the breast. Then in 2003, a study   claimed that antiperspirant/deodorant use and underarm shaving were associated with an earlier age of breast cancer diagnosis. Finally, a 2005 article reported a significant and linear increase in breast cancer located in the upper outer quadrant over the period 1979– 2000, an area closer to the armpit and presumably more exposed to aluminum deposits from cosmetic use. These publications created a hypothesis that the aluminum contained in antiperspirants causes breast cancer. There isn’t strong evidence to support that antiperspirants with aluminum cause cancer.   As a consequence, several studies have been conducted to determine whether there is a link between aluminum-containing antiperspirants and breast cancer. Most of the epidemiologic studies conducted to date have not produced consistent results on this association. There are mixed results, but no article with high quality evidence proving the correlation. The claim that the incidence in the upper outer quadrant increases over time has not been confirmed . Other evidences suggests that there is no association, such as the non-increase in the incidence of bilateral breast cancer. If the product is applied to both armpits, it should increase the incidence of bilateral breast cancer, but this was not the case. In addition, men also use these products, so we should find an increased incidence of breast cancer among them. But we didn’t. Although there is some biological evidence that aluminum has some carcinogenic potential when tested in vitro and in animal models, the human body is far more complex than these tests can capture. This evidence isn't strong enough. What do the American Cancer Society and the National Cancer Institute say? In the meantime, the American Cancer Society has stated: “There are no conclusive epidemiologic studies (studies in humans) linking breast cancer risk to antiperspirant use, and very little scientific evidence to support this claim”. The National Institutes of Cancer say: “no scientific evidence links the use of these products to the development of breast cancer”. Our recommendation regarding aluminum in antiperspirants So, the conclusion is not categorical: aluminum probably does not cause breast cancer. This might not be the answer that you were expecting but it’s what science is saying far. Since it is still a subject in debate, if you want to be extra careful it is prudent to reduce exposure to aluminum and avoid application on injured or irritated skin. Written By Luis Guilherme

In a letter to Robert Hooke in 1675, Isaac Newton made his most famous statement: “If I have seen further it is by standing on the shoulders of Giants”. This statement captures the essence of scientific progress. Progressive discoveries made by the most tenacious of us. To highlight Gynaecological Cancer Awareness Month, we will dig into the history of one of these giants, whose discovery changed the landscape of women's health forever.      Overcoming Early Setbacks Dr. Georgios Papanikolaou, was a physician and researcher born in Greece in 1883. He moved to the United States in 1913. Initially struggling to make ends meet, the physician had to work in a carpet store. It took him a while until he was finally admitted to the staff at Cornell University’s medical college in New York City. But, Papanikolaou's early assignment was far from glamorous: he was tasked with studying the menstrual cycles of guinea pigs. Over time, however, this seemingly mundane work turned into a deep understanding of cervical cells. Papanikolaou meticulously observed how these cells changed in shape according to hormonal fluctuations, eventually allowing him to predict the exact stage of a guinea pig's menstrual cycle. Building on this knowledge, he began applying his techniques to human subjects. By analyzing the morphology of cells from the human uterus, he could also predict the stages of the menstrual cycle. Despite a decade of obsessive research, these findings offered little practical benefit, as simpler methods already existed for this purpose. Papanikolaou realized that the true potential of his work lay not in analyzing healthy cells but in identifying pathological conditions. He began collecting samples from women with various diseases. In the late 1920s, while examining cells from women with cervical cancer, he made a groundbreaking observation: cancerous cells could be detected in vaginal fluid. He published his results in 1928 in an article titled " New Cancer Diagnosis ". However, the medical community criticized his findings and even mocked his suggestion. They already had better methods for detecting cervical cancer. After two decades of obsessively analyzing cervical cells, his two findings were useless. But his perseverance was not over.    Identifying cancer before symptoms even appear Undeterred, Papanikolaou spent the next two decades refining his technique and gathering more evidence to support his hypothesis. His routine involved countless hours peering into a microscope, analyzing women’s vaginal smears with limited support. It wasn't until years later that he fully understood the profound implications of his work: his technique was not for detecting cancer but for identifying cancer before symptoms even appeared. Cervical cell analysis could detect cancerous cells years before any physical symptoms, allowing for much earlier intervention. His research culminated in the 1943 publication of " Diagnosis of Uterine Cancer by the Vaginal Smear. " This work provided the first comprehensive evidence that regular screening with the Pap test could detect cervical cancer at a pre-symptomatic stage, significantly improving the chances of successful treatment. Armed with this evidence, Papanikolaou convinced the National Cancer Institute to undertake the largest cancer prevention studies ever. 150,000 women from Shelby County, Tennessee, were screened using the Pap test. As a result, 555 cases of cervical cancer were detected, and more importantly, 557 asymptomatic women were found to have early-stage cervical cancer. The average age of these early-detected women was two decades younger than those diagnosed with advanced cancer, meaning the Pap test advanced their diagnosis by nearly 20 years, providing them with significantly better treatment outcomes. Long-lasting Impact on Women's Health The introduction of the Pap test marked a seismic shift in the fight against cervical cancer. Before its development, cervical cancer was one of the leading causes of cancer-related deaths among women, often diagnosed only when it was too late for effective treatment. The Pap test empowered women and healthcare providers by offering a simple, non-invasive method to detect abnormal cells early before they could develop into cancer. This early detection capability drastically reduced cervical cancer mortality rates and became a model for other cancer screening programs. However, the legacy of Georgios Papanikolaou’s discovery extends far beyond the Pap test itself. His work underscored the importance of early detection in cancer prevention, inspiring the introduction of other screening programs, such as the introduction of mammography.  As we reflect on the groundbreaking work of Dr. Georgios Papanikolaou and the life-saving potential of early detection, it's crucial to remember the importance of following recommended screening guidelines. Today, the Pap test is recommended every three years for women from 21 to 29, every five years for women from 29 to 65, and for women over 65, if they’re considered low-risk, screening may stop. Unfortunately, there are no screening tests for other GYN cancers, but genetic testing might help identify a predisposition to develop ovarian cancer. Regular screenings, such as the Pap test, OB-GYN visits, and genetic testing are vital tools of modern medicine to empower us to detect cancers early or even a predisposition to them. Early detection saves lives. Written By Luis Guilherme

Prostate cancer remains the most common cancer diagnosis among men and the second most common diagnosis overall, with an estimated 300,000 new cases expected this year in the United States alone. Despite the high number of diagnoses, it remains one of the less fatal forms of cancer. The overall 5-year relative survival is 96.9%. But that wasn’t always the case. To highlight Prostate Cancer Awareness Month, let's dive deep into the discovery of the Prostate-Specific Antigen (PSA), a test that has played a crucial role in shifting the landscape of prostate cancer detection and treatment. The Accidental Discovery of PSA: A Turning Point in Prostate Cancer Detection The history of PSA (prostate-specific antigen), now a key tool in prostate cancer detection, began with an unexpected finding. In the 1960s, researchers noted a protein present in prostate tissue and seminal fluid. In 1966, Mitsuwo Hara, a Japanese forensic scientist, identified this protein hoping it could serve as forensic evidence. However, Hara's work did not gain much traction beyond this initial discovery. In the 1970s, other scientists studying male infertility came across the same protein. Some even speculated that it might have cancer-fighting properties, but for over a decade, its potential role in cancer detection was largely ignored. From Fertility Research to Cancer Diagnosis It wasn’t until the early 1980s that a research team led by Dr. T. Ming Chu at Roswell Park Cancer Institute recognized the protein’s significance. They discovered that men with prostate cancer had elevated levels of PSA in their blood. This breakthrough revolutionized prostate cancer diagnosis, leading to FDA approval of the PSA test in 1986 for monitoring prostate cancer patients. By 1994, the test was approved for widespread early detection. What began as fertility research serendipitously became a cornerstone of cancer diagnostics, allowing for earlier identification and treatment of prostate cancer, significantly improving patient outcomes. Prostate Cancer Survival: The Power of Early Detection The impact of early detection on prostate cancer survival is undeniable. According to data from the SEER database, men diagnosed with localized or regional prostate cancer between 2013 and 2019 had a 5-year relative survival rate of over 99%. This impressive statistic shows that when prostate cancer is caught early, before it spreads beyond the prostate, treatment is highly successful, giving men an excellent chance of long-term survival.  The Impact of PSA Testing on Prostate Cancer Mortality The dramatic decrease in prostate cancer mortality over the last few decades can be attributed largely to the widespread use of PSA testing. Research supports the idea that PSA testing has caused a stage shift in how prostate cancer is diagnosed. Before the PSA test was introduced, many men were diagnosed in more advanced stages of the disease, when treatment options were limited, and survival rates are lower. With the advent of PSA screening, more men are diagnosed in earlier stages, when the disease is more treatable, and the chances of survival are significantly higher. This shift from late-stage detection to early-stage diagnosis has led to remarkable improvements in prognosis and contributed to the steady decline in prostate cancer mortality. The Future of PSA Testing and Beyond Although the PSA test has transformed prostate cancer care, its limitations continue to drive research toward more precise screening methods. Although the test has saved countless lives through early detection, it is not without its challenges. The PSA test has led to the detection of many slow-growing, non-lethal prostate cancers, raising concerns about overdiagnosis and overtreatment. Despite these concerns, the PSA test has remained the gold standard in prostate cancer screening for over 30 years.  Researchers are exploring new biomarkers, genomic testing, and imaging technologies to improve prostate cancer detection and better differentiate between aggressive and non-aggressive cancers. These advancements aim to reduce over-diagnosis and provide men with more accurate, personalized treatment options. Conclusion There is no single centralized clinical guideline for Prostate Cancer in the USA. The American Cancer Society recommends that men make an informed decision about prostate cancer screening in consultation with their healthcare provider. Key points include: Age for discussion: 50 for men at average risk 45 for men at high risk (e.g., African American men, or those with a first-degree relative diagnosed before 65) 40 for men at very high risk (more than one first-degree relative diagnosed at a young age) Screening tests: The PSA blood test is recommended, with a digital rectal exam (DRE) as an option. Timing of screenings: Every 2 years if PSA is less than 2.5 ng/mL Annually if PSA is 2.5 ng/mL or higher PSA is a powerful story of how early detection can save lives. The discovery of the PSA test revolutionized prostate cancer diagnosis, transforming it from a once-deadly disease into one where early detection offers a 99% chance of survival. As we observe Prostate Cancer Awareness Month, it's a reminder of the progress we've made and the importance of continued vigilance in screening and research. Written By Luis Guilherme

In this picture: Dr. Chasse Bailey-Dorton , Medical Director, and Mariana Arnaut, CEO As we celebrate Cancer Research Day, an often-overlooked challenge remains: survivorship care. Survivorship is not just about surviving beyond a cancer diagnosis; it’s about patients being able to live fully in a world forever changed by it. Over the past decades, the number of cancer survivors has grown exponentially, an indicator to advancements in early detection and treatment. However, this progress brings new responsibilities for healthcare and society as a whole. Survivors face long-term physical, emotional, and mental challenges that often fall outside the scope of traditional oncology care. Research shows that many survivors experience ongoing health issues, ranging from fatigue to cognitive impairments. Survivors also have a higher risk of recurrence and chronic conditions. Unfortunately, our current healthcare system is not fully equipped to support these patients. There’s a shortage of oncologists and nurses for follow-ups, and primary care providers are unfamiliar with cancer’s complexities. This all contributes to gaps in care and highlights an urgent need to establish an innovative approach to survivorship within the cancer care continuum. At The After Cancer , we believe that survivorship care must be personalized, comprehensive and start at the point of diagnosis. Our approach focuses on harnessing technology and expert clinical insights to create care plans that evolve with each survivor's needs. By integrating cutting-edge technology and compassionate human touch, we aim to address the gaps that survivors face, ensuring they have access to comprehensive care and everyday support, not just on and off medical interventions. Survivorship care isn't just an add-on; it’s a necessity. Whether it’s addressing mental health, managing long-term side effects, or reducing the risk of recurrence, every survivor deserves a roadmap to a healthier future. Our mission is to make that survivorship care accessible for anyone, anywhere, anytime. The future of cancer care is about more than saving lives. It's about giving patients the tools to fully live, not just survive, after cancer. Survivorship is our priority. Is it yours? About Mariana Arnaut Mariana Arnaut is the CEO and Co-Founder of The After Cancer. She has a family history of different cancers (lung, melanoma, esophageal) and a background in digital & innovation. You can reach out to her at mariana@theaftercancer.com .

Written by: Jessie Nash, Program Manager, Go Jen Go Foundation Navigating breast cancer can be challenging, but knowing what to expect and how to manage things can make a big difference. When newly diagnosed you are receiving a lot of information, going to many doctors appointments, all while processing the news and emotions that come with a breast cancer diagnosis.  6 tips to help you navigate a breast cancer diagnosis Understand Your Diagnosis and Treatment Plan : Take time to learn about your specific type of breast cancer, its stage, and the recommended treatments. Don’t hesitate to ask your healthcare team for detailed explanations and written information about all of your options. Be open with your healthcare team about concerns and symptoms. Build a Support System : Reach out to family, friends, or support groups. See if your healthcare team has any support groups, services or knows of local organizations for you to find connection and support. Connecting with others who have had similar experiences can provide comfort and practical advice. Keep Track of Appointments and Medications : To help you stay organized and not miss anything, use a planner, app, or journal to manage your medical appointments, treatment schedule, and medications.  Manage Side Effects & Prioritize Your Care : Discuss potential side effects of your treatment with your doctor and plan how to manage them. Focus on maintaining a healthy diet , staying hydrated, and getting enough rest. Gentle exercise , if approved by your doctor, can also be beneficial. Seek Financial and Practical Help : Look into resources that can assist with medical expenses, transportation, and other practical needs. Many organizations offer support for patients undergoing treatment. Explore Complementary Therapies : Some patients find therapies like acupuncture, massage, or meditation helpful for managing stress and side effects. Always discuss these options with your doctor first. Your healthcare team is built up of many different people from nurses, doctors, surgeons and other support staff. Your nurse navigator is a great person to help you navigate the complex journey of cancer treatment and to help you find the resources you need. 4 ways your nurse navigator can support you Guidance Through the Healthcare System : Nurse navigators help patients understand and navigate the complex healthcare system. They assist with scheduling appointments, coordinating tests, and ensuring that the patient receives timely and appropriate care. Plus they can help with education and information about your diagnosis. Emotional Support : Nurse navigators offer emotional support and reassurance. They listen to patients' concerns, help them cope with anxiety and fear, and provide comfort during challenging times. Care Coordination : They act as a central point of contact for the patient’s care team, ensuring that all providers are on the same page.  Resource Connection : They connect patients with additional resources, such as support groups, counseling services, and educational materials, which can be beneficial for both emotional and practical support. Remember, each person's breast cancer journey is unique , so it's important to find what works best for you. About Go Jen Go The Go Jen Go Foundation is a Charlotte, NC nonprofit providing hope and critical support to families who are facing the financial burden of a breast cancer diagnosis within the greater Charlotte area. Our programming helps cover household expenses including housing, utilities, transportation, and groceries/necessities while a patient undergoes breast cancer treatment. In addition, our Mood Williams Camp Scholarship fund provides camp opportunities for our grantees’ children, while our Operation Spread the Joy Program uplifts families by delivering gifts during the holiday season.   The organization was co-founded by Joe & Jen Pagani, a Charlotte mom who saw an unmet need in our community during her 6 1/2-year battle with breast cancer. With over $1.5 million granted to local patients, Jen's legacy continues as we help cover the day-to-day finances so families can focus on their fight against breast cancer. Learn more about Go Jen Go at www.gojengo.org .

October is Breast Cancer Awareness Month, a time when communities come together to raise awareness, provide support, and fund critical research for breast cancer. North Carolina hosts several impactful and inspiring events that support breast cancer patients, survivors, and their families. Whether you’re looking to walk, run, or attend educational sessions, here are some of the best breast cancer events to consider attending in October 2024. 1. Pink Cupcake Walk - Charlotte Date:  October 5th 12, 2024 Location:  Symphony Park at SouthPark, Charlotte Info:   https://runsignup.com/Race/NC/Charlotte/TasteofCharlotteCupcakeWalk A fun, family-friendly event, the Pink Cupcake Walk  is one of Charlotte’s most delicious ways to support breast cancer awareness. Participants walk to raise funds and awareness for breast cancer while enjoying cupcakes along the way! This whimsical event encourages everyone, from families with kids to breast cancer survivors and supporters, to come together for a sweet cause. The proceeds benefit local breast cancer organizations and provide much-needed support for those battling the disease. Costumes and pink-themed attire are highly encouraged to add to the festive spirit! 2. Making Strides Against Breast Cancer - Charlotte Date:  October 19, 2024 Location:  First Ward Park, Charlotte Info: https://secure.acsevents.org/site/STR?pg=entry&fr_id=108755 Making Strides Against Breast Cancer in Charlotte is a hallmark event that unites survivors, supporters, and families for an inspiring day of hope and action. This walk is about more than just raising funds—it’s about empowering survivors, sharing stories of resilience, and building community support. In addition to the walk, participants can enjoy live music, activities for families, and opportunities to honor those affected by breast cancer. Funds raised go to support research and breast cancer programs through the American Cancer Society. 3. Making Strides Against Breast Cancer - Triangle Date:  October 26, 2024 Location:  North Hills, Raleigh Info: https://secure.acsevents.org/site/STR?pg=entry&fr_id=108809 For those in the Raleigh area, the Triangle’s Making Strides event is equally powerful. This walk brings together the local community to raise awareness and support for breast cancer research, treatment, and patient care. Like the Charlotte event, this is more than just a walk—it's a chance to support survivors, honor loved ones, and stand up against breast cancer in a united front. 4. 2024 Komen Charlotte More Than Pink Walk in Charlotte Date:  October 26, 2024 Location:  Symphony Park at SouthPark Mall, Charlotte Info: https://secure.info-komen.org/site/SPageNavigator/mtpw_home.html?fr_id=10534 The Susan G. Komen More Than Pink Walk is another iconic breast cancer event. Susan G Jomen events are dedicated to raising funds for breast cancer research, community outreach, and patient support programs. Participants come together to honor survivors and remember those who lost their battle with breast cancer. 5. Pose for Pink Fashion Show in Wilmington Date:  October 12, 2024 Location:  Going Beyond the Pink, Wilmington Info: https://www.goingbeyondthepink.org/events This Pose for Pink Fashion Show, hosted by Going Beyond the Pink, is a fantastic way to connect with a supportive community of patients and survivors. The event features members hitting the runway to showcase the hottest fall looks and glamorous formal wear. This inspirational event is a great opportunity to support local breast cancer initiatives. Why Attend These Events? Breast cancer awareness events offer more than just an opportunity to support a worthy cause—they create a sense of community, inspire hope, and remind us of the importance of early detection, research, and support for those affected by breast cancer. Whether you’re walking for a loved one, learning about survivorship, or simply enjoying cupcakes with friends, every event contributes to a larger movement working to fight breast cancer. With so many options across North Carolina, there’s something for everyone this October. Join in, make a difference, and help change the future of breast cancer care. About Mariana Arnaut Mariana Arnaut  is the CEO and Co-Founder  of The After Cancer. She has a family history of different cancers (lung, melanoma, esophageal) and a background in digital & innovation. You can reach out to her at mariana@theaftercancer.com .

October is Breast Cancer Awareness Month, a time to unite communities, raise awareness, and support breast cancer patients, survivors, and their families. South Carolina hosts several inspiring events throughout the month, providing opportunities to walk, run, and educate yourself about breast cancer. Here are some of the best breast cancer events to attend in South Carolina in October 2024. 1. Making Strides Against Breast Cancer - Myrtle Beach Date:  October 12, 2024 Location:  Crown Reef Beach Resort, Myrtle Beach Info:   https://secure.acsevents.org/site/STR?pg=entry&fr_id=109229 Join the fight against breast cancer at Making Strides Against Breast Cancer  in Myrtle Beach. This event is a 5K walk that unites breast cancer survivors, caregivers, and supporters for an inspiring day filled with hope. The funds raised go directly toward the American Cancer Society’s breast cancer research and patient programs. Expect a powerful experience with live music, survivor recognition, and opportunities to honor those who have battled the disease. It’s a family-friendly event where participants of all ages can get involved. 2. Making Strides Against Breast Cancer - Charleston Date:  October 26, 2024 Location:  Johns Island County Park Info:   https://secure.acsevents.org/site/STR?pg=entry&fr_id=108807 Join the fight against breast cancer at Making Strides Against Breast Cancer  in Charloeston. This event is a 5K walk that unites breast cancer survivors, caregivers, and supporters for an inspiring day filled with hope. The funds raised go directly toward the American Cancer Society’s breast cancer research and patient programs. Expect a powerful experience with live music, survivor recognition, and opportunities to honor those who have battled the disease. It’s a family-friendly event where participants of all ages can get involved. Pink Promenade Catwalk & Cocktails Date:  October 12, 2024 Location:  Mount Pleasant, Towne Centre Info: https://www.mtpleasanttownecentre.com/events/pink-promenade-catwalk-cocktails/ In observance of Breast Cancer Awareness Month, Towne Centre and Roper St. Francis Healthcare present their 6th annual Pink Promenade, a special catwalk + cocktails fundraiser to benefit the Roper St. Francis Foundation Breast Cancer Program. After the fashion show guests can shop with their exclusive Pink Pass Shopping Passport which includes special offers from Towne Centre retailers along with raffles and giveaways. Why Attend These Events? Attending breast cancer events in South Carolina during October not only supports research and raises awareness but also offers an opportunity to connect with survivors, families, and advocates. Whether you’re walking, running, or enjoying a concert or gala, each event contributes to the larger fight against breast cancer. You’ll be part of a community that’s making a difference—one step, one story, and one contribution at a time. So, get involved, show your support, and help make October 2024 a month to remember in the fight against breast cancer! About Mariana Arnaut Mariana Arnaut  is the CEO and Co-Founder  of The After Cancer. She has a family history of different cancers (lung, melanoma, esophageal) and a background in digital & innovation. You can reach out to her at mariana@theaftercancer.com .